A step closer to artificial livers: Researchers identify compounds that help liver cells grow outside body

A step closer to artificial livers: Researchers identify compounds that help liver cells grow outside body

June 2, 2013 — Prometheus, the mythological figure who stole fire from the gods, was punished for this theft by being bound to a rock. Each day, an eagle swept down and fed on his liver, which then grew back to be eaten again the next day.

Modern scientists know there is a grain of truth to the tale, says MIT engineer Sangeeta Bhatia: The liver can indeed regenerate itself if part of it is removed. However, researchers trying to exploit that ability in hopes of producing artificial liver tissue for transplantation have repeatedly been stymied: Mature liver cells, known as hepatocytes, quickly lose their normal function when removed from the body.

"It's a paradox because we know liver cells are capable of growing, but somehow we can't get them to grow" outside the body, says Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science at MIT, a senior associate member of the Broad Institute and a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science.

Now, Bhatia and colleagues have taken a step toward that goal. In a paper appearing in the June 2 issue of Nature Chemical Biology, they have identified a dozen chemical compounds that can help liver cells not only maintain their normal function while grown in a lab dish, but also multiply to produce new tissue.

Cells grown this way could help researchers develop engineered tissue to treat many of the 500 million people suffering from chronic liver diseases such as hepatitis C, according to the researchers.

Lead author of the paper is Jing (Meghan) Shan, a graduate student in the Harvard-MIT Division of Health Sciences and Technology. Members of Bhatia's lab collaborated with researchers from the Broad Institute, Harvard Medical School and the University of Wisconsin.

Large-scale screen

Bhatia has previously developed a way to temporarily maintain normal liver-cell function after those cells are removed from the body, by precisely intermingling them with mouse fibroblast cells. For this study, funded by the National Institutes of Health and Howard Hughes Medical Institute, the research team adapted the system so that the liver cells could grow, in layers with the fibroblast cells, in small depressions in a lab dish. This allowed the researchers to perform large-scale, rapid studies of how 12,500 different chemicals affect liver-cell growth and function.

The liver has about 500 functions, divided into four general categories: drug detoxification, energy metabolism, protein synthesis and bile production. David Thomas, an associate researcher working with Todd Golub at the Broad Institute, measured expression levels of 83 liver enzymes representing some of the most finicky functions to maintain.

After screening thousands of liver cells from eight different tissue donors, the researchers identified 12 compounds that helped the cells maintain those functions, promoted liver cell division, or both.

Two of those compounds seemed to work especially well in cells from younger donors, so the researchers -- including Robert Schwartz, an IMES postdoc, and Stephen Duncan, a professor of human and molecular genetics at the University of Wisconsin -- also tested them in liver cells generated from induced pluripotent stem cells (iPSCs). Scientists have tried to create hepatocytes from iPSCs before, but such cells don't usually reach a fully mature state. However, when treated with those two compounds, the cells matured more completely.

Bhatia and her team wonder whether these compounds might launch a universal maturation program that could influence other types of cells as well. Other researchers are now testing them in a variety of cell types generated from iPSCs.

In future studies, the MIT team plans to embed the treated liver cells on polymer tissue scaffolds and implant them in mice, to test whether they could be used as replacement liver tissues. They are also pursuing the possibility of developing the compounds as drugs to help regenerate patients' own liver tissues, working with Trista North and Wolfram Goessling of Harvard Medical School.

Eric Lagasse, an associate professor of pathology at the University of Pittsburgh, says the findings represent a promising approach to overcoming the difficulties scientists have encountered in growing liver cells outside of the body. "Finding a way of growing functional hepatocytes in cell culture would be a major breakthrough," says Lagasse, who was not part of the research team.

Making connections

Bhatia and colleagues have also recently made progress toward solving another challenge of engineering liver tissue, which is getting the recipient's body to grow blood vessels to supply the new tissue with oxygen and nutrients. In a paper published in the Proceedings of the National Academy of Sciences in April, Bhatia and Christopher Chen, a professor at the University of Pennsylvania, showed that if preformed cords of endothelial cells are embedded into the tissue, they will rapidly grow into arrays of blood vessels after the tissue is implanted.

To achieve this, Kelly Stevens in the Bhatia lab worked with Peter Zandstra at the University of Toronto to design a new system that allows them to create 3-D engineered tissue and precisely control the placement of different cell types within the tissue. This approach, described in the journal Nature Communications in May, allows the engineered tissue to function better with the host tissue.

"Together, these papers offer a path forward to solve two of the longstanding challenges in liver tissue engineering -- growing a large supply of liver cells outside the body and getting the tissues to graft to the transplant recipient," Bhatia says.

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Printing innovations provide 10-fold improvement in organic electronics

Printing innovations provide 10-fold improvement in organic electronics

Organic electronics have great promise for a variety of applications, but even the highest quality films available today fall short in how well they conduct electrical current. The team from the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory and Stanford University have developed a printing process they call FLUENCE -- fluid-enhanced crystal engineering -- that for some materials results in thin films capable of conducting electricity 10 times more efficiently than those created using conventional methods.

"Even better, most of the concepts behind FLUENCE can scale up to meet industry requirements," said Ying Diao, a SLAC/Stanford postdoctoral researcher and lead author of the study, which appeared today in Nature Materials.

Stefan Mannsfeld, a SLAC materials physicist and one of the principal investigators of the experiment, said the key was to focus on the physics of the printing process rather than the chemical makeup of the semiconductor. Diao engineered the process to produce strips of big, neatly aligned crystals that electrical charge can flow through easily, while preserving the benefits of the "strained lattice" structure and "solution shearing" printing technique previously developed in the lab of Mannsfeld's co-principal investigator, Professor Zhenan Bao of the Stanford Institute for Materials and Energy Sciences, a joint SLAC-Stanford institute.

To make the advance, Diao focused on controlling the flow of the liquid in which the organic material is dissolved. "It's a vital piece of the puzzle," she said. If the ink flow does not distribute evenly, as is often the case during fast printing, the semiconducting crystals will be riddled with defects. "But in this field there's been little research done on controlling fluid flow."

Diao designed a printing blade with tiny pillars embedded in it that mix the ink so it forms a uniform film. She also engineered a way around another problem: the tendency of crystals to randomly form across the substrate. A series of cleverly designed chemical patterns on the substrate suppress the formation of unruly crystals that would otherwise grow out of alignment with the printing direction. The result is a film of large, well-aligned crystals.

X-ray studies of the group's organic semiconductors at the Stanford Synchrotron Radiation Lightsource (SSRL) allowed them to inspect their progress and continue to make improvements, eventually showing neatly arranged crystals at least 10 times longer than crystals created with other solution-based techniques, and of much greater structural perfection.

The group also repeated the experiment using a second organic semiconductor material with a significantly different molecular structure, and again they saw a notable improvement in the quality of the film. They believe this is a sign the techniques will work across a variety of materials.

Principal investigators Bao and Mannsfeld say the next step for the group is pinning down the underlying relationship between the material and the process that enabled such a stellar result. Such a discovery could provide an unprecedented degree of control over the electronic properties of printed films, optimizing them for the devices that will use them.

"That could lead to a revolutionary advance in organic electronics," Bao said. "We've been making excellent progress, but I think we're only just scratching the surface."

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Printing innovations provide ten-fold improvement in organic electronics

Printing innovations provide ten-fold improvement in organic electronics

June 2, 2013 — Through innovations to a printing process, researchers have made major improvements to organic electronics -- a technology in demand for lightweight, low-cost solar cells, flexible electronic displays and tiny sensors. The printing method is fast and works with a variety of organic materials to produce semiconductors of strikingly higher quality than what has so far been achieved with similar methods.

Organic electronics have great promise for a variety of applications, but even the highest quality films available today fall short in how well they conduct electrical current. The team from the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory and Stanford University have developed a printing process they call FLUENCE -- fluid-enhanced crystal engineering -- that for some materials results in thin films capable of conducting electricity 10 times more efficiently than those created using conventional methods.

"Even better, most of the concepts behind FLUENCE can scale up to meet industry requirements," said Ying Diao, a SLAC/Stanford postdoctoral researcher and lead author of the study, which appeared today in Nature Materials.

Stefan Mannsfeld, a SLAC materials physicist and one of the principal investigators of the experiment, said the key was to focus on the physics of the printing process rather than the chemical makeup of the semiconductor. Diao engineered the process to produce strips of big, neatly aligned crystals that electrical charge can flow through easily, while preserving the benefits of the "strained lattice" structure and "solution shearing" printing technique previously developed in the lab of Mannsfeld's co-principal investigator, Professor Zhenan Bao of the Stanford Institute for Materials and Energy Sciences, a joint SLAC-Stanford institute.

To make the advance, Diao focused on controlling the flow of the liquid in which the organic material is dissolved. "It's a vital piece of the puzzle," she said. If the ink flow does not distribute evenly, as is often the case during fast printing, the semiconducting crystals will be riddled with defects. "But in this field there's been little research done on controlling fluid flow."

Diao designed a printing blade with tiny pillars embedded in it that mix the ink so it forms a uniform film. She also engineered a way around another problem: the tendency of crystals to randomly form across the substrate. A series of cleverly designed chemical patterns on the substrate suppress the formation of unruly crystals that would otherwise grow out of alignment with the printing direction. The result is a film of large, well-aligned crystals.

X-ray studies of the group's organic semiconductors at the Stanford Synchrotron Radiation Lightsource (SSRL) allowed them to inspect their progress and continue to make improvements, eventually showing neatly arranged crystals at least 10 times longer than crystals created with other solution-based techniques, and of much greater structural perfection.

The group also repeated the experiment using a second organic semiconductor material with a significantly different molecular structure, and again they saw a notable improvement in the quality of the film. They believe this is a sign the techniques will work across a variety of materials.

Principal investigators Bao and Mannsfeld say the next step for the group is pinning down the underlying relationship between the material and the process that enabled such a stellar result. Such a discovery could provide an unprecedented degree of control over the electronic properties of printed films, optimizing them for the devices that will use them.

"That could lead to a revolutionary advance in organic electronics," Bao said. "We've been making excellent progress, but I think we're only just scratching the surface."

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Printing innovations provide ten-fold improvement in organic electronics

Printing innovations provide ten-fold improvement in organic electronics

June 2, 2013 — Through innovations to a printing process, researchers have made major improvements to organic electronics -- a technology in demand for lightweight, low-cost solar cells, flexible electronic displays and tiny sensors. The printing method is fast and works with a variety of organic materials to produce semiconductors of strikingly higher quality than what has so far been achieved with similar methods.

Organic electronics have great promise for a variety of applications, but even the highest quality films available today fall short in how well they conduct electrical current. The team from the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory and Stanford University have developed a printing process they call FLUENCE -- fluid-enhanced crystal engineering -- that for some materials results in thin films capable of conducting electricity 10 times more efficiently than those created using conventional methods.

"Even better, most of the concepts behind FLUENCE can scale up to meet industry requirements," said Ying Diao, a SLAC/Stanford postdoctoral researcher and lead author of the study, which appeared today in Nature Materials.

Stefan Mannsfeld, a SLAC materials physicist and one of the principal investigators of the experiment, said the key was to focus on the physics of the printing process rather than the chemical makeup of the semiconductor. Diao engineered the process to produce strips of big, neatly aligned crystals that electrical charge can flow through easily, while preserving the benefits of the "strained lattice" structure and "solution shearing" printing technique previously developed in the lab of Mannsfeld's co-principal investigator, Professor Zhenan Bao of the Stanford Institute for Materials and Energy Sciences, a joint SLAC-Stanford institute.

To make the advance, Diao focused on controlling the flow of the liquid in which the organic material is dissolved. "It's a vital piece of the puzzle," she said. If the ink flow does not distribute evenly, as is often the case during fast printing, the semiconducting crystals will be riddled with defects. "But in this field there's been little research done on controlling fluid flow."

Diao designed a printing blade with tiny pillars embedded in it that mix the ink so it forms a uniform film. She also engineered a way around another problem: the tendency of crystals to randomly form across the substrate. A series of cleverly designed chemical patterns on the substrate suppress the formation of unruly crystals that would otherwise grow out of alignment with the printing direction. The result is a film of large, well-aligned crystals.

X-ray studies of the group's organic semiconductors at the Stanford Synchrotron Radiation Lightsource (SSRL) allowed them to inspect their progress and continue to make improvements, eventually showing neatly arranged crystals at least 10 times longer than crystals created with other solution-based techniques, and of much greater structural perfection.

The group also repeated the experiment using a second organic semiconductor material with a significantly different molecular structure, and again they saw a notable improvement in the quality of the film. They believe this is a sign the techniques will work across a variety of materials.

Principal investigators Bao and Mannsfeld say the next step for the group is pinning down the underlying relationship between the material and the process that enabled such a stellar result. Such a discovery could provide an unprecedented degree of control over the electronic properties of printed films, optimizing them for the devices that will use them.

"That could lead to a revolutionary advance in organic electronics," Bao said. "We've been making excellent progress, but I think we're only just scratching the surface."

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Innovative new nanotechnology stops bed bugs in their tracks -- literally

Innovative new nanotechnology stops bed bugs in their tracks -- literally

May 30, 2013 — Bed bugs now need to watch their step. Researchers at Stony Brook University have developed a safe, non-chemical resource that literally stops bed bugs in their tracks. This innovative new technology acts as a human-made web consisting of microfibers 50 times thinner than a human hair which entangle and trap bed bugs and other insects. This patent-pending technology is being commercialized by Fibertrap, a private company that employs non-toxic pest control methods.

The nanotech solution was developed at Stony Brook University's Center for Advanced Technology in Sensor Materials (Sensor CAT), a program funded by NYSTAR, as part of a statewide effort to encourage greater technological and economic collaboration between industry and research universities.

Miriam Rafailovich "Our nanotechnology produces entanglements that are millions of times more dense than woven products such as fabrics or carpets," said lead researcher Miriam Rafailovich, Distinguished Professor of Materials Science and Engineering and Co-Director in the Program of Chemical and Molecular Engineering at Stony Brook University. "The microfibers trap them by attaching to microstructures on their legs taking away their ability to move, which stops them from feeding and reproducing."

Successful tests were performed using live bed bugs and termites in Professor Rafailovich's lab with the assistance of Ying Liu, a scientist with Stony Brook University's Advanced Energy Research and Technology Center and Stony Brook graduate students Shan He and Linxi Zhang.

Kevin McAllister, Fibertrap's co-founder added, "We are very excited to move this advancement from the lab to the consumer. Our goal has always been to make a difference for people living in areas where bed bugs are pervasive and difficult to eradicate."

The microfibers are safe for humans and pets and unlike chemical treatments the insects cannot develop a resistance to it.

About Bed Bugs

Bed bugs (Cimex lectularius) are small, flat, parasitic insects that feed solely on the blood of people and animals while they sleep. Bed bugs are reddish-brown in color, wingless, range from one millimeter (mm) to seven mm (roughly the size of Lincoln's head on a penny), and can live several months without a blood meal.

Infestation

Bed bug infestations usually occur around or near the areas where people sleep. These areas include apartments, shelters, rooming houses, hotels, cruise ships, buses, trains and dorm rooms. They hide during the day in places such as seams of mattresses, box springs, bed frames, headboards, dresser tables, inside cracks or crevices, behind wallpaper or any other clutter or objects around a bed. Bed bugs have been shown to be able to travel over 100 feet in a night but tend to live within eight feet of where people sleep. A bed bug bite affects each person differently. Bite responses can range from an absence of any physical signs of the bite, to a small bite mark, to a serious allergic reaction. Bed bugs are not considered to be dangerous; however, an allergic reaction to several bites may need medical attention. (Source: Centers for Disease Control and Prevention) For more information please check out the Centers for Disease Control and Prevention Bed Bug FAQs.

Statistics

New York City consistently ranks in the top 10 or 15 cities with the worst bed bug problem across the nation. An annual list released by Orkin Pest Control based upon bed bug business in U.S. cities, lists Chicago as having the worst bed bug problem for 2012; New York City comes in at #10.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Researchers coax clays to make human bone

Researchers coax clays to make human bone

The NDSU research team's 3-D mesh scaffold is composed of degradable materials that are compatible to human tissue. Over time, the cells generate bone and the scaffold deteriorates. As indicated in the NDSU team's published scientific research from 2008 to 2013, the nanoclays enhance the mechanical properties of the scaffold by enabling scaffold to bear load while bone generates. An interesting finding by the Katti group has shown that the nanoclays also impart useful biological properties to the scaffold.

"The biomineralized nanoclays also impart osteogenic or bone-forming abilities to the scaffold to enable birth of bone," said Dr. Kalpana Katti, Distinguished Professor of civil engineering at NDSU. "Although it would have been exciting to say that this finding had a 'Eureka moment,' this discovery was a methodical exploration of simulations and modeling, indicating that amino acid modified nanoclays are viable new nanomaterials," said Katti. The work was initially published in the Journal of Biomacromolecules in 2005. The current findings point toward the potential use of nanoclays for broader applications in medicine.

The NDSU's group most recent study in the Journal of Biomedical Materials Research Part A, published online Feb. 15, 2013, reports that nanoclays mediate human mesenchymal stem cell differentiation into bone cells and grow bone. The Katti research group uses amino acids, the building blocks of life, to modify clay structures and the modified nanoclays coax new bone growth. "Our current research studies underway involve the use of bioreactors that mimic fluid/blood flow in the human body during bone tissue regeneration," said Dr. Kalpana Katti.

The Katti group at NDSU has pioneered the use of nanoclays in bone regeneration since 2008, with research results appearing in Biomedical Materials, ASME Journal of Nanotechnology for Engineering and Medicine, Materials Science and Engineering C, along with the February 2013 publication in the Journal of Biomedical Materials Research Part A.

Bone tissue engineering represents important promise for regenerative medicine, according to Dr. Kalpana Katti. National Institutes of Health information shows that more than one million Americans have a hip or knee replaced each year. An aging population, in addition to orthopedic injuries of military veterans, and diseases such as osteoporosis and arthritis mean that the promise of scientific research to generate human bone could have far-reaching implications in the future.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Innovative new nanotechnology stops bed bugs in their tracks -- literally

Innovative new nanotechnology stops bed bugs in their tracks -- literally

May 30, 2013 — Bed bugs now need to watch their step. Researchers at Stony Brook University have developed a safe, non-chemical resource that literally stops bed bugs in their tracks. This innovative new technology acts as a human-made web consisting of microfibers 50 times thinner than a human hair which entangle and trap bed bugs and other insects. This patent-pending technology is being commercialized by Fibertrap, a private company that employs non-toxic pest control methods.

The nanotech solution was developed at Stony Brook University's Center for Advanced Technology in Sensor Materials (Sensor CAT), a program funded by NYSTAR, as part of a statewide effort to encourage greater technological and economic collaboration between industry and research universities.

Miriam Rafailovich "Our nanotechnology produces entanglements that are millions of times more dense than woven products such as fabrics or carpets," said lead researcher Miriam Rafailovich, Distinguished Professor of Materials Science and Engineering and Co-Director in the Program of Chemical and Molecular Engineering at Stony Brook University. "The microfibers trap them by attaching to microstructures on their legs taking away their ability to move, which stops them from feeding and reproducing."

Successful tests were performed using live bed bugs and termites in Professor Rafailovich's lab with the assistance of Ying Liu, a scientist with Stony Brook University's Advanced Energy Research and Technology Center and Stony Brook graduate students Shan He and Linxi Zhang.

Kevin McAllister, Fibertrap's co-founder added, "We are very excited to move this advancement from the lab to the consumer. Our goal has always been to make a difference for people living in areas where bed bugs are pervasive and difficult to eradicate."

The microfibers are safe for humans and pets and unlike chemical treatments the insects cannot develop a resistance to it.

About Bed Bugs

Bed bugs (Cimex lectularius) are small, flat, parasitic insects that feed solely on the blood of people and animals while they sleep. Bed bugs are reddish-brown in color, wingless, range from one millimeter (mm) to seven mm (roughly the size of Lincoln's head on a penny), and can live several months without a blood meal.

Infestation

Bed bug infestations usually occur around or near the areas where people sleep. These areas include apartments, shelters, rooming houses, hotels, cruise ships, buses, trains and dorm rooms. They hide during the day in places such as seams of mattresses, box springs, bed frames, headboards, dresser tables, inside cracks or crevices, behind wallpaper or any other clutter or objects around a bed. Bed bugs have been shown to be able to travel over 100 feet in a night but tend to live within eight feet of where people sleep. A bed bug bite affects each person differently. Bite responses can range from an absence of any physical signs of the bite, to a small bite mark, to a serious allergic reaction. Bed bugs are not considered to be dangerous; however, an allergic reaction to several bites may need medical attention. (Source: Centers for Disease Control and Prevention) For more information please check out the Centers for Disease Control and Prevention Bed Bug FAQs.

Statistics

New York City consistently ranks in the top 10 or 15 cities with the worst bed bug problem across the nation. An annual list released by Orkin Pest Control based upon bed bug business in U.S. cities, lists Chicago as having the worst bed bug problem for 2012; New York City comes in at #10.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Researchers coax clays to make human bone

Researchers coax clays to make human bone

The NDSU research team's 3-D mesh scaffold is composed of degradable materials that are compatible to human tissue. Over time, the cells generate bone and the scaffold deteriorates. As indicated in the NDSU team's published scientific research from 2008 to 2013, the nanoclays enhance the mechanical properties of the scaffold by enabling scaffold to bear load while bone generates. An interesting finding by the Katti group has shown that the nanoclays also impart useful biological properties to the scaffold.

"The biomineralized nanoclays also impart osteogenic or bone-forming abilities to the scaffold to enable birth of bone," said Dr. Kalpana Katti, Distinguished Professor of civil engineering at NDSU. "Although it would have been exciting to say that this finding had a 'Eureka moment,' this discovery was a methodical exploration of simulations and modeling, indicating that amino acid modified nanoclays are viable new nanomaterials," said Katti. The work was initially published in the Journal of Biomacromolecules in 2005. The current findings point toward the potential use of nanoclays for broader applications in medicine.

The NDSU's group most recent study in the Journal of Biomedical Materials Research Part A, published online Feb. 15, 2013, reports that nanoclays mediate human mesenchymal stem cell differentiation into bone cells and grow bone. The Katti research group uses amino acids, the building blocks of life, to modify clay structures and the modified nanoclays coax new bone growth. "Our current research studies underway involve the use of bioreactors that mimic fluid/blood flow in the human body during bone tissue regeneration," said Dr. Kalpana Katti.

The Katti group at NDSU has pioneered the use of nanoclays in bone regeneration since 2008, with research results appearing in Biomedical Materials, ASME Journal of Nanotechnology for Engineering and Medicine, Materials Science and Engineering C, along with the February 2013 publication in the Journal of Biomedical Materials Research Part A.

Bone tissue engineering represents important promise for regenerative medicine, according to Dr. Kalpana Katti. National Institutes of Health information shows that more than one million Americans have a hip or knee replaced each year. An aging population, in addition to orthopedic injuries of military veterans, and diseases such as osteoporosis and arthritis mean that the promise of scientific research to generate human bone could have far-reaching implications in the future.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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IC Distributor:http://www.suvsystem.com/l/IC(Integrated-Circuits)-1.html

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SUV System Ltd insists on the managing faith ofsincereness,speciality,foresight, win-win,so we build up stable-relationship customers located all over the world, including the States, Europe, Argentina, UAE, Malaysia, Australia,and India etc

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Satellites support drones in commercial airspace

Satellites support drones in commercial airspace

A demonstration involved the deployment of a Heron-1 RPAS controlled by satellite for maritime surveillance applications offshore Spain. The project demonstrated the safe operation of RPAS in non-segregated airspace using satellite communications. Several partners, such as the GUCI (Spanish "Guardia Civil") and AENA (Aeropuertos Españoles y Navegación Aérea), supported the project.

The demonstration was part of the DeSIRE (Demonstration of Satellites enabling the Insertion of RPAS in Europe) initiative, an ESA-EDA (European Space Agency-European Defence Agency) project which includes European headquartered satellite operator SES, together with partners such as ThalesAleniaSpace and AT-one (an European Economic Interest Group consisting of Dutch Aerospace Laboratory NLR and German Aerospace Centre DLR). The initiative follows another ESA study (ESA SINUE) during which SES was already partnering with INDRA, the Spanish information technology and defense systems company.

Read the full story on EE Times Europe.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Satellites support drones in commercial airspace

Satellites support drones in commercial airspace

A demonstration involved the deployment of a Heron-1 RPAS controlled by satellite for maritime surveillance applications offshore Spain. The project demonstrated the safe operation of RPAS in non-segregated airspace using satellite communications. Several partners, such as the GUCI (Spanish "Guardia Civil") and AENA (Aeropuertos Españoles y Navegación Aérea), supported the project.

The demonstration was part of the DeSIRE (Demonstration of Satellites enabling the Insertion of RPAS in Europe) initiative, an ESA-EDA (European Space Agency-European Defence Agency) project which includes European headquartered satellite operator SES, together with partners such as ThalesAleniaSpace and AT-one (an European Economic Interest Group consisting of Dutch Aerospace Laboratory NLR and German Aerospace Centre DLR). The initiative follows another ESA study (ESA SINUE) during which SES was already partnering with INDRA, the Spanish information technology and defense systems company.

Read the full story on EE Times Europe.

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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Intel wins CPU slot in Samsung tablet

Intel wins CPU slot in Samsung tablet

LONDON – Samsung Electronics will use Atom-branded processors from Intel Corp. in a range of budget Android tablet computers, according to reports from Reuters and the Korea Times.

Samsung has chosen an Intel Clover Trail processor for at least one version of its Galaxy Tab 3 10.1, the Reuters report said. Clover Trial is a version of the Atom processor implemented in 32-nm CMOS.

The breakthrough by Intel into the mobile computing market is important for the company which has previously dominated personal computing but struggled to gain traction in the mobile sector. However, it is also unusual as Samsung is itself a developer and vendor of mobile processors, under the Exynos brand.

The Galaxy Tab 3 is expected to be unveiled at the Computex exhibition in Taiwan held during the first week of June.

Intel's design win was secured partly due to its willingness to offer favorable pricing and partly on its ability to provide resources to help with design work, according to the Korea Times report.

"Samsung wants to secure as many processors as possible at better pricing. That’s why Samsung Electronics has recently been diversifying its procurement channel in processor chips as a strategy to stabilize production yields of its in-house Exynos-branded processors," the Korea Times quoted a unnamed member of the Samsung research staff saying.

The same report cited an unnamed Intel Korea source saying that Intel had increased the number of chip engineers designing around the Atom processor from 6 to 50. "Most of them are working for Samsung-related projects with a mission to customize circuits for adaptation on Samsung products,” the report quoted the source saying.


Related links and articles:

Qualcomm leads smartphone processor market

London Calling: PowerVR confirmed in Samsung's 'Octa'

Intel chooses Dialog PMIC for 'Bay Trail' processor

Welcome to SUV System Ltd!

SUV System Ltd is ISO 90012008 Certified electronics distributor with 10 years of experiences.

We have built up long term business relationship with about many companies which are stockers and authorized agents. we have a steady and reliable supply to meet customer's demands to the greatest extent .Confidently, we are able to lower your cost and support your business with our years of professional service.

SUV System Ltd is Electronic Components Distributor Supplies,Find Quality Electronic Components Supplies Products IC(Integrated Circuits),Connectors,Capacitor,Resistors,Diodes,Transistors,LED at Suvsystem.com. Sourcing Other Energy, Environment, Excess Inventory Products from Manufacturers and Suppliers at Suvsystem.com

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